Oxytrol (oxybutynin) reduces muscle spasms of the bladder and urinary tract.

Oxytrol transdermal skin patch is used to treat symptoms of overactive bladder such as frequent or urgent urination, incontinence (urine leakage), and increased nighttime urination.

Oxytrol patches may also be used for purposes not listed in this medication guide.

Use Oxytrol skin patches exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Oxytrol comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Open the sealed pouch and remove the protective liner. Apply the Oxytrol patch to a clean, dry area on your stomach, hip or buttock. Avoid skin that is irritated or damaged, or skin that has been treated with oil or lotion. Avoid placing the patch on a skin area that will be rubbed by a waistband or tight clothing.

Press the Oxytrol patch firmly into place with your fingers. You may leave the patch on while bathing, showering, or swimming.

If an Oxytrol patch falls off, try sticking back into place. If it does not stick well, put on a new patch and leave it on only for the rest of your wearing time. Do not change your patch removal schedule.

Leave the Oxytrol patch in place and wear it for 3 to 4 days. You should change the patch twice per week (such as every Sunday and Thursday). Use a calendar to help you keep a steady patch-changing schedule.

Choose a different place on your skin to wear the patch each time you put on a new one. Do not use the same skin area twice within 7 days.

Do not wear more than one Oxytrol patch at a time. Using extra skin patches will not make the medicine more effective. Never cut a skin patch.

Use baby oil or mild soap and water to remove any adhesive residue that stays on your skin. Avoid using harsh soaps, alcohol, nail polish remover, or other solvents that could irritate your skin.

After removing a patch, fold it in half so it sticks together and throw it away in a place where children or pets cannot get to it.

The Oxytrol patch may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the patch before undergoing such a test.

Keep the Oxytrol patch in its sealed pouch until you are ready to use it. Store the pouches at room temperature away from heat and moisture.

You should not use Oxytrol if you have uncontrolled narrow-angle glaucoma, a blockage in your stomach or intestines, or if you are unable to urinate.+

You should not use Oxytrol skin patches if you are allergic to oxybutynin, or if you have:

• untreated or uncontrolled narrow-angle glaucoma;
• a blockage in your digestive tract (stomach or intestines); or
• if you have decreased urination or are unable to urinate.

To make sure Oxytrol is safe for you, tell your doctor if you ever have:

• glaucoma;
• liver or kidney disease;
• myasthenia gravis;
• an enlarged prostate;
• an intestinal disorder, such as ulcerative colitis;
• a stomach disorder such as hiatal hernia, gastroesophageal reflux disease (GERD), or slow digestion; or
• trouble emptying your bladder.

Oxytrol is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether oxybutynin transdermal passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Get emergency medical help if you have any signs of an allergic reaction to Oxytrol: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Oxytrol patches and call your doctor at once if you have:

• little or no urinating;
• severe constipation;
• confusion, hallucinations;
• vomiting, severe heartburn or upper stomach pain;
• fast or uneven heart rate; or
• dehydration symptoms - feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin.

Common Oxytrol side effects may include:

• dizziness, drowsiness;
• redness or mild skin itching where a patch was worn;
• dry mouth;
• blurred vision; or
• constipation, diarrhea, decreased urination.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

What happens if I miss a dose?

If you forget to change a patch on your scheduled day, remove and replace the patch as soon as you remember. Wear the patch until your next regular patch-changing day. Do not change your schedule, even if you wear the new patch for fewer that 3 days.

Do not apply two patches at the same time to make up the missed dose.

What should I avoid while using Oxytrol?

Oxybutynin can cause blurred vision, drowsiness, or dizziness. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Drinking alcohol can increase certain side effects of oxybutynin.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Drink plenty of fluids to keep yourself hydrated while you are using Oxytrol patches. Oxybutynin can decrease sweating and you may be more prone to heat stroke.

Do not expose the Oxytrol patch to sunlight. It should be worn under clothing.

What other drugs will affect Oxytrol?

Using this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking a sleeping pill, opioid pain medication, muscle relaxer, or medicine for anxiety, depression, or seizures.

Tell your doctor about all your current medicines and any you start or stop using during your treatment with Oxytrol patches, especially:

• cold or allergy medicine that contains an antihistamine;
• medicine for Parkinson's disease;
• medicine to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel syndrome;
• bronchodilators - aclidinium, ipratropium, or tiotropium;
• medicine to treat osteoporosis or Paget's disease of bone - alendronate, etidronate, ibandronate, pamidronate, risedronate, tiludronate, zoledronic acid; or
• other bladder or urinary medicines - darifenacin, fesoterodine, oral oxybutynin, tolterodine, solifenacin.

This list is not complete. Other drugs may interact with oxybutynin transdermal, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.