Naratriptan is used to treat the symptoms of migraine headaches (severe, throbbing headaches that sometimes are accompanied by nausea and sensitivity to sound or light). Naratriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels around the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that cause pain, nausea, and other symptoms of migraine. Naratriptan does not prevent migraine attacks or reduce the number of headaches you have.

Naratriptan comes as a tablet to take by mouth. It is usually taken at the first sign of a migraine headache. If your symptoms improve after you take naratriptan but return after 4 hours or longer, you may take a second tablet. However, if your symptoms do not improve after you take naratriptan, do not take a second tablet before calling your doctor. Your doctor will tell you the maximum number of tablets you may take in a 24-hour period. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take naratriptan exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Amergeis contraindicated in patients with ischemic or vasospastic CAD. There have been rare reports of serious cardiac adverse reactions, including acute myocardial infarction, occurring within a few hours following administration of AMERGE. Some of these reactions occurred in patients without known CAD. AMERGE may cause coronary artery vasospasm (Prinzmetal's angina) even in patients without a history of CAD. If you are at high risk for heart disease, your doctor may want to check your heart before prescribing naratriptan. Naratriptan has caused serious side effects in some people, especially people who have heart or blood vessel disease. Be sure that you discuss with your doctor the risks of using this medicine as well as the benefits.

The following adverse reactions are discussed in more detail in other sections of the prescribing information:

- Myocardial ischemia, myocardial infarction, and Prinzmetal's angina

- Arrhythmias Chest, throat, neck, and/or jaw pain/tightness/pressure Cerebrovascular events Other vasospasm reactions

- Medication overuse headache

- Serotonin syndrome

- Increase in blood pressure

- Hypersensitivity reactions

This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.

How often can you take Amerge?

The recommended dose of Amerge is 1 mg or 2.5 mg. If the migraine returns or if the patient has the only partial response, the dose may be repeated once after 4 hours, for a maximum dose of 5 mg in a 24-hour period.

Does naratriptan cause drowsiness?

Naratriptan may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you. Talk to your doctor about your headache symptoms to make sure they are caused by migraines.

Can naratriptan cause high blood pressure?

Naratriptan can raise blood pressure to dangerous levels. Your blood pressure may need to be checked often while you are using this medicine.

Does naratriptan make you sleepy?

Naratriptan can make you feel sleepy. If this happens, do not drive and do not use tools or machines