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What is Wellbutrin XL?

Wellbutrin XL is an antidepressant that is used to treat the major depressive disorder, seasonal affective disorder, and other conditions. Wellbutrin XL contains bupropion which works by restoring the balance of natural chemicals in your brain such as norepinephrine and dopamine.

Always follow your doctor’s directions about taking medication.
Before using this medication, read the enclosed information and instructions.

  • Wellbutrin XL can be taken with or without food but taking it with or after a meal can help to prevent stomach upset.
  • Take Wellbutrin XL in the morning to prevent sleeping problems.
  • Swallow Wellbutrin XL whole without crushing or chewing the capsules.
  • It can take up to four weeks for Wellbutrin XL to be most effective.
  • Do not stop taking Wellbutrin without speaking to your doctor, unless you are having a seizure.

Cautions

Tell your doctor:

  • Any prescription or over-the-counter medications that you take.
  • Your medical history especially of seizures, brain tumors, brain injuries, head injuries, other conditions that may increase the risk of seizures, heart disease, kidney problems, liver disease, diabetes, hereditary glaucoma, or high blood pressure.
  • If you have any drug or other allergies.
  • If you are pregnant or planning pregnancy.
  • If you have ever had an eating disorder.
  • About your history of alcohol and drug use.

You should also know:

  • Older adults may be more sensitive to the side effects of this medication.
  • Wellbutrin XL can have undesirable effects on children who are breast-feeding.
  • This medication can cause dizziness. Avoid driving or any other activity requiring alertness unless you can do it safely.

Side Effects of Wellbutrin XL

Common side effects of Wellbutrin XL:

  • Nausea or vomiting.
  • Headaches or dizziness.
  • Sore throat or dry mouth.
  • Problems sleeping.
  • Loss of appetite or weight loss.
  • Ringing in your ears.
  • Increased sweating.
  • Shaking.
  • Constipation.
  • An empty tablet shell in your stool.

Seek medical help if you experience any of these bupropion side effects:

  • Signs of an allergic reaction such as hives, breathing difficulties, or swelling in your face, lips, or throat.
  • Fast, irregular, or pounding heartbeat.
  • Raised blood pressure.
  • Seizures.
  • Unusual weight gain or loss.
  • Eye pain, redness, or swelling.
  • Widened eye pupils.
  • Changes to your vision including seeing rainbows around lights or blurred vision.
  • Mood or mental changes such as unusual thinking or behavior, anxiety, agitation, memory loss, or confusion.

FAQs

What should I do if I miss my dose of Wellbutrin XL?

If you miss your Wellbutrin XL dose, take it when you remember. Skip the missed dose if it is almost time for your next dose.

What is the strength of Wellbutrin XL?

Both Wellbutrin XL and the generic alternative Bupropion XL are available in strengths of 150mg and 300mg.

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Ron M

September 11, 2026

Service is great

Joe S

September 11, 2026

Even tho I’m a republican I vote for who’s the best fit for my life. Apparently we will have to see if his trump rx covers mt Eliquis. But until then you people have been of great support for me and straight up with the cost, shipping time country of origin. Nothing but complete admiration for Canada med. Thank you immensely.

Gayle C

September 11, 2026

The gentleman that called was nice and very helpful. Explained all my options. I appreciate the calls I receive, as reminders. I purchased 1 years worth of meds. I have been with this company for over 3+ years and never had any issues.

Hollis M

September 11, 2026

Prompt, friendly, courteous and efficient - got it all.

Bobbi M

September 11, 2026

The packaging was always great and arrived within the expected time frame. The personal was always very prompt in notifying me when it was time to order my next refill and they were always friendly and professional. I have appreciated my involvement with your company.

Melinda

September 11, 2026

My husband and I are both saving close to 50 percent on Apixaban. Being able to get the generic brand makes a big difference. The customer service is friendly and professional. I feel like we are in good hands. And I like doing business with our neighbors in Canada. The thought and reality that this is changing due to US politics is very disturbing. I hope it works out sooner than later and apologize for the ridiculous policies of this US administration.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-248-1511 and a member of our CareTeam will be happy to assist you.

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* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.